It is NOT recommended! The cause of facial wrinkles is the repetitive movement of the under lying facial muscles. If you stretch out the skin and attempt to pre-flatten the targeted wrinkle zones before applying the patches it causes tension in the facial muscles, they are not able to relax and naturally fill in the wrinkle lines over time with repeated use. Also, stretching out the skin is like pulling on a rubber band, stretching the skin creates tension which the patch maintains until it is peeled off. The skin will snap back into place and could make your wrinkle lines more severe.